Wednesday, August 20, 2025

You have options

Yes, you can incorporate both NRP (NeuroImaging PREProcessing toolS) and TIFF files within the same project 
NRP tools, such as fMRIPrep, are designed to generate minimally preprocessed neuroimaging data that are ready for further analysis, according to NiPreps (https://www.nipreps.org/nipreps-book/nipreps/nipreps.html). These tools are meant to be agnostic to downstream analysis, meaning they don't perform operations like spatial smoothing which are tied to specific statistical models. [1, 2, 3]  
TIFF (Tagged Image File Format) files are commonly used for storing image data, including medical and scientific images. [4, 5, 6]  
How they can work together: 

• Input for NRP tools: You might start with raw neuroimaging data in formats that can be processed by NRP tools, potentially including data from various imaging modalities that are ultimately converted to or managed within a project that can also handle TIFF images. 
• Outputs from NRP tools: NRP tools generate preprocessed data, which can then be visualized and analyzed further. While the direct output format of NRP tools might not always be TIFF, the preprocessed data can be used to generate visualizations that can be saved in TIFF format or be part of a larger project that incorporates TIFF images for other purposes. 
• Visualization and Integration: 

 • TIFF images are excellent for displaying neuroimaging results, such as statistical maps, anatomical overlays, or various slices generated from the preprocessed data. 
 • Many visualization tools and software packages commonly used in neuroscience and related fields support both neuroimaging data formats (which NRP tools might handle internally or output) and TIFF images. 
 • Tools like ImageJ/Fiji, QuPath, Napari, CellProfiler, and even some programming languages with libraries like Python's or can read, process, and display TIFF files alongside analysis data derived from NRP workflows. [7, 8, 9, 10, 11]  

Examples: 

• Generating anatomical atlases in TIFF: You might use NRP tools to process raw MRI scans and then generate anatomical atlases or regions of interest that can be saved as TIFF files for visualization and comparison with other data. 
• Overlaying functional data on anatomical TIFFs: You could take functional activation maps generated from NRP-processed fMRI data and overlay them onto high-resolution anatomical images stored as TIFF files for comprehensive visualization. 
• Integrating microscopy and neuroimaging data: If your project involves both microscopy images (often stored as TIFFs) and neuroimaging data, you can use NRP tools for the neuroimaging component and then integrate the results with the microscopy data for a more holistic analysis. [12, 13, 14]  

In summary, NRP tools prepare neuroimaging data for analysis, while TIFF files are suitable for storing images, including visualizations and other image-based data within a project. The outputs from NRP tools can be visualized and combined with TIFF files for various research and analysis purposes. [15, 16]  

AI responses may include mistakes.

[1] https://www.nipreps.org/nipreps-book/nipreps/nipreps.html[2] https://www.nipreps.org/nipreps-book/nipreps/nipreps.html[3] https://pmc.ncbi.nlm.nih.gov/articles/PMC7762845/[4] https://www.peernet.com/best-file-formats-for-business-tasks/[5] https://digitize.library.ubc.ca/digitizers-blog/how-we-digitize-microfilm/[6] https://expertphotography.com/tiff-vs-jpeg-vs-raw/[7] https://www.narps.info/analysis.html[8] https://www.nature.com/articles/nmeth.4326[9] https://pmc.ncbi.nlm.nih.gov/articles/PMC11968550/[10] https://www.rockefeller.edu/bioimaging/image-analysis-data-management/[11] https://pmc.ncbi.nlm.nih.gov/articles/PMC11160600/[12] https://www.protocols.io/view/pipeline-for-image-processing-and-quantification-o-4r3l2qojpl1y/v1[13] https://pmc.ncbi.nlm.nih.gov/articles/PMC7366126/[14] https://pmc.ncbi.nlm.nih.gov/articles/PMC4332798/[15] https://www.nature.com/articles/s41596-023-00881-0[16] https://pubmed.ncbi.nlm.nih.gov/37816904/


Henry McClure  
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Topeka Kansas

Mayor Mike Padilla is exiting stage left. That alone tells a story. He is leaving behind rising utility rates that the city locked in for 2024 through 2026, with 2025's increases already baked into the published rate sheets. Voters are not imagining higher water, wastewater, and stormwater bills. They were approved, scheduled, and posted, and residents are paying them right now.  

City Manager Robert Perez talks about stability while senior staff heads keep rolling. In the span of days this month, the city attorney resigned, the city planning director resigned, and Perez issued statements to calm nerves. When your legal counsel and your planning lead walk out in the middle of budget season and housing initiatives, "we're steady" does not pass the laugh test.  

Deputy Mayor Brett Kell was elevated by his colleagues back in January to run meetings and help set the agenda. Fine. Where is the visible win residents can feel on their street or on their bill? As deputy, his job is to move basics faster, not narrate them. The record so far is ceremonies and promises while the city scrambles more pothole crews and still holds hearings on the same aging-infrastructure problems.   

The governing body keeps touting "planning" and "engagement." Translation in Topeka has been more meetings, more hearings, and more rate models. The FY2025 budget was marketed as structurally balanced, which is good, but residents notice what is balanced on their back. Every family that opened a higher utility bill this year understands the difference between a slide deck and a result. 

Here is the kicker. Barely one in ten voters even showed up for the primary. That is not civic pride, that is civic fatigue. If the current cast were inspiring confidence, turnout would not be stuck under ten percent. The city deserves leadership that earns attention without a crisis.

Henry McClure  
785.383.9994
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Fwd: SPECIAL Transient Guest Tax Committee Meeting-August 27, 2025



---------- Forwarded message ---------
From: City of Topeka, Kansas <no-reply@topeka.org>
Date: Wed, Aug 20, 2025 at 4:25 PM
Subject: SPECIAL Transient Guest Tax Committee Meeting-August 27, 2025
To: <mcre13@gmail.com>


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You are receiving this because you asked to be notified when City of Topeka shares City Council Committee related information.

A SPECIAL Transient Guest Tax Committee meeting has been scheduled for Wednesday, August 27, 2025 at 10:00am. The meeting will be held in the 1st Floor Conference Room of the Cyrus K. Holliday Building (620 SE Madison). Please contact the Council office by 10:00am on 8/26 to obtain the virtual log-in information. The meeting will be live-streamed on the City of Topeka's Facebook and City4 Communications platforms as well.

Please view the Public Meeting calendar for agenda information: https://www.topeka.org/calendar/

Additional City Council information including the meeting agenda is located at https://www.topeka.org/citycouncil/

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Henry McClure 
Time kills deals
785-383-9994

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this is good

Marisol Marcelo
While it's easy to point out what's wrong, I believe it's just as important to recognize that our local leaders are human too. This is their first time living and leading, just like it is for all of us. When we extend grace, patience, and constructive feedback, we create space for growth and collaboration. Together, we can help shape a stronger Topeka.


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Henry McClure 
Time kills deals
785-383-9994

www.henrymcclure.live
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Re: ​KORA Request for Voter Count and Details on $9.5 Million ATT Building Allocation

The vote count for the Go Topeka Board was listed as a percentage. 

I want a roll call. 

I want each name and how they voted.

We deserve transparency. 

H 

On Wed, Aug 20, 2025 at 2:57 PM Stephanie Moran <stephanie.moran@topekapartnership.com> wrote:

The official meeting minutes from the GO Topeka Board Meeting on December 3, 2024 were provided via email on July 11th per the KORA request sent by Mr. McClure on July 8th.

 

 

From: Henry McClure <mcre13@gmail.com>
Sent: Tuesday, August 19, 2025 7:41 PM
To: City Clerk <cclerk@topeka.org>; Molly Howey (Go Topeka) <mhowey@gotopeka.com>; Molly Howey <molly.howey@topekapartnership.com>; Molly Howey <mhowey@topekachamber.org>; Stephanie Moran <stephanie.moran@topekapartnership.com>; countyclerk@snco.us; MCRE Media <mcre1.snco@blogger.com>; Governing Body <governingbody@topeka.org>
Subject: ​KORA Request for Voter Count and Details on $9.5 Million ATT Building Allocation

 



Under the Kansas Open Records Act (KORA), I am requesting the specific voter count and detailed information regarding the individuals who voted on the allocation of $9.5 million for the ATT building at the Go Topeka meeting held prior to the December JEDO meeting. While a percentage breakdown of the vote has been provided, the public is entitled to transparency regarding the individual voting records and how each member voted on this matter.
Please provide the requested information in accordance with KORA requirements. Thank you for your attention to this request.

 



--
Henry McClure 
Time kills deals
785-383-9994

www.henrymcclure.live
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